Drosophila Zic family member odd-paired is needed for adult post-ecdysis maturation
نویسندگان
چکیده
منابع مشابه
The Zic family member, odd-paired, regulates the Drosophila BMP, decapentaplegic, during adult head development.
The eye/antennal discs of Drosophila form most of the adult head capsule. We are analyzing the role of the BMP family member decapentaplegic (dpp) in the process of head formation, as we have identified a class of cis-regulatory dpp mutations (dpp(s-hc)) that specifically disrupts expression in the lateral peripodial epithelium of eye/antennal discs and is required for ventral head formation. H...
متن کاملThe Zic family homologue Odd-paired regulates Alk expression in Drosophila
The Anaplastic Lymphoma Kinase (Alk) receptor tyrosine kinase (RTK) plays a critical role in the specification of founder cells (FCs) in the Drosophila visceral mesoderm (VM) during embryogenesis. Reporter gene and CRISPR/Cas9 deletion analysis reveals enhancer regions in and upstream of the Alk locus that influence tissue-specific expression in the amnioserosa (AS), the VM and the epidermis. B...
متن کاملHyzic, the Hydra homolog of the zic/odd-paired gene, is involved in the early specification of the sensory nematocytes.
Cnidaria are the first class of organisms in animal evolution with a nervous system. The cnidarian Hydra has two types of neuronal cell, nerve cells and nematocytes. Both differentiate from the same pool of pluripotent stem cells. Yet, the molecular regulation of neural differentiation in Hydra is largely unknown. Here, we report the identification of Hyzic, a homolog of the Zn-finger transcrip...
متن کاملThe RED domain of Paired is specifically required for Drosophila accessory gland maturation
The evolutionarily conserved paired domain consists of the N-terminal PAI and the C-terminal RED domains, each containing a helix-turn-helix motif capable of binding DNA. Despite its conserved sequence, the physiological functions of the RED domain remain elusive. Here, we constructed a prd transgene expressing a truncated Paired (Prd) protein without the RED domain, and examined its rescue abi...
متن کاملA novel member of the Xenopus Zic family, Zic5, mediates neural crest development
We characterized Xenopus Zic5 which belongs to a novel class of the Zic family. Zic5 is more specifically expressed in the prospective neural crest than other Zic genes. Overexpression of Zic5 in embryos led to ectopic expression of the early neural crest markers, Xsna and Xslu, with the loss of epidermal marker expression. In Zic5-overexpressing animal cap explants, there was marked induction ...
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ژورنال
عنوان ژورنال: Open Biology
سال: 2019
ISSN: 2046-2441
DOI: 10.1098/rsob.190245